Myke Payne🔺

If you love to cook, you need to check this recipe for risotto. Do yourself a favor and make one for your fam. Recipe by chef Gordon Ramsay. Ingredients needed for the risotto: 100g Arborio rice (use top quality like Carnroli or Nano) 25g white onion, finely diced 20g coconut oil 125g fresh garden peas 40g fresh garden peas, pureed 350ml vegetable stock Salt and pepper to taste 1 mint sprig Pea shoots For the mint oil: 1 bunch of mint 400ml extra virgin olive oil Recipe for the mint oil: Wash the bunch of mint and pat dry. Strip the leaves from the stalks and lay out onto an oven tray. Heat at around 80°C for 2-3 hours to dry out the leaves. Add the mint leaves and olive oil to a saucepan. On a very low heat, warm the olive oil for 1 hour until the oil is green. Blitz the oil in a blender and pass through muslin or very fine sieve. You will then have a beautiful clear mint oil, which you can drizzle around the risotto. Recipe for the risotto: Add the coconut oil to a saucepan pan and sweat the onions on a medium-low heat until tender and translucent. Do not allow to colour or brown. Add the Arborio rice to the onion and stir to coat the grains in oil. Add half of the stock to the pan and bring to a gentle simmer. Ensure it retains a constant heat and gently stir as it cooks – it should take around 20 minutes. As the rice absorbs the water and begins to swell, add the remaining liquid gradually as it is absorbed. Season with a little salt and pepper. Meanwhile, in a blender, add 40g of the fresh garden peas with a splash of water and pulse into a puree. When the rice is tender, add the mint sprig. Remove from the heat and gently stir in the pea puree, and fresh peas. Mix through, remove the mint sprig and season to taste with salt and pepper. Serve into a bowl and dress with pea shoots, and a drizzle of mint oil.

A personalized mRNA vaccine for pancreatic cancer has shown remarkable potential in clinical trials. It triggered long-lasting immune responses that could prevent the disease from ever returning. For decades, pancreatic cancer has been one of the most lethal and difficult-to-treat malignancies, notorious for its high recurrence rate even after successful surgical removal. However, a groundbreaking Phase 1 clinical trial of a personalized mRNA vaccine, known as autogene cevumeran, offers a beacon of hope. Led by researchers at the Memorial Sloan Kettering Cancer Center, the trial evaluated the vaccine’s ability to train patients' immune systems to recognize and destroy microscopic, post-surgery cancer cells. The vaccine works by analyzing each patient’s tumor to identify specific mutations, creating a custom mRNA blueprint that prompts the body to produce cancer-fighting T cells. The results have been remarkably encouraging: the vaccine successfully triggered a robust, long-lasting immune response in half of the study participants. Follow-up data presented in 2026 revealed that those patients who mounted an immune response experienced a significantly lower risk of cancer recurrence, with nearly 90% of these 'responders' still alive up to six years post-treatment. This milestone marks a critical shift toward proactive, highly targeted cancer interception and paves the way for larger clinical trials aimed at transforming the prognosis for pancreatic cancer patients worldwide. source: Balachandran, V. P., et al. Personalized RNA neoantigen vaccines stimulate T cells in pancreatic cancer.

Poland made it official: those convicted of abusing minors under 15, or of sexual crimes against close relatives, will have to undergo chemical castration before regaining their freedom. A judge orders the hormone treatment, which reduces sexual desire but also causes erectile dysfunction, loss of bone mass, and mood changes. For some, it is the only real way to curb repeat offenses and protect victims. For others, it is corporal punishment disguised as medicine that opens a dangerous door regarding the limits of the State over a person’s body. Is it necessary justice or a precedent that no country should normalize?

A neurologist at Mount Sinai Health System reportedly gave a patient an unusual exercise: stick out the tongue fully for 40 seconds, twice a day. Within weeks, the patient’s stress markers improved dramatically. Why would something so simple matter? The neck and jaw are major storage sites for chronic tension. That tension can influence breathing patterns, posture, and nervous-system regulation. The tongue connects to the hyoid bone, which anchors deep muscles throughout the throat and neck. Extending the tongue may help release tension across this fascial chain, encouraging relaxation and reducing the body’s constant “fight-or-flight” signaling. The idea is simple: sometimes stress isn’t just psychological—it’s physical. Small shifts in breathing, posture, and muscle tension can send signals of safety back to the nervous system. Disclaimer: This content is for informational purposes only and is not medical advice, diagnosis, or treatment. Always consult a qualified healthcare professional before making changes to your health routine.

It's just a PC Until you realize it's powered by a Ryzen 9 9950X3D RTX 5090, and 128GB RAM. Then it's no longer just a PC. It's a monster

All MaD Here

A chewing gum was engineered to remove a virus and bacteria that can cause cancer. Researchers at the University of Pennsylvania developed the gum from lablab beans, which naturally contain an antiviral protein called FRIL. When extracts from the gum were mixed with saliva collected from people with head and neck cancer, they trapped and removed an average of 93% of detectable HPV. In oral rinse samples, HPV levels fell by about 80%. The team then added an antimicrobial peptide called protegrin-1 to target two bacteria associated with head and neck cancer: Porphyromonas gingivalis and Fusobacterium nucleatum. A single treatment reduced both bacteria by more than 99% while having little effect on beneficial oral bacteria. HPV can cause changes in infected cells that lead to several cancers, including cancers of the throat, mouth and cervix. The two bacterial species do not directly prove that cancer will develop, but high levels have been associated with inflammation, tumor progression and poorer outcomes in some patients. The idea behind the gum is simple: chewing could release antiviral and antibacterial proteins directly into the mouth, keeping them in contact with the target microbes. But this is not yet a cancer treatment. The gum extracts were tested on saliva and oral rinse samples outside the body. Participants did not chew the gum as part of this study, and researchers did not test whether it prevented infections, shrank tumors or improved survival. Clinical trials are still needed to determine whether the gum works safely in people. HPV vaccination remains the proven way to prevent the infections responsible for most HPV-related cancers. Still, the findings suggest that something as ordinary as chewing gum could eventually become an affordable way to deliver medicine directly inside the mouth. Read the study: “Ex vivo HNSCC clinical studies using saliva and antiviral or antibacterial chewing gums reveal reduction in carcinogenic microbes.” Scientific Reports

Scary😭